Functional analysis of mutations of murine chromosome 17 with the use of tertiary trisomy.

doi:10.1093/genetics/127.4.781

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Article

Functional analysis of mutations of murine chromosome 17 with the use of tertiary trisomy.

Genetics - 1 Apr 1991

Ruvinsky A, Agulnik A, Agulnik S, Rogachova M

Abstract excerpt

Analysis of the functional nature of mutations can be based on comparisons of their manifestation in organisms with a deletion or duplication of a particular chromosome segment. With the use of reciprocal translocation T(16;17)43H, it is feasible to produce mice with tertiary trisomy of the proximal region of chromosome 17. The mutations on chromosome 17 we tested included brachyury (T), hairpin tail (Thp), kinky...

Topics

Alleles
Animals
Chromosome Deletion
Chromosome Mapping
Crosses, Genetic
Genes, Dominant
Genes, Lethal
Genes, Recessive
Genotype
Haplotypes
Karyotyping
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred Strains

Mutation

Phenotype

Tail

Translocation, Genetic

Trisomy

Source

Open in PubMed Open full text

Identifiers

PMID: 2029971
DOI: 10.1093/genetics/127.4.781
PMCID: PMC1204405

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2029971-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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