Article
The DNA target sequence influences the dependence of the yeast transcriptional activator Gcn4 on co-factors.
Molecular & general genetics : MGG - 27 Feb 1997
Tavernarakis N, Thireos G
Abstract excerpt
The yeast transcriptional activator Gcn4 requires the Ada2/Gcn5/Ada3 co-activator complex to exert part of its activation potential. Here we show that the sequence of the DNA target modulates the function of Gcn4 by modifying this requirement. Promoter configurations were generated that rendered...
Topics
- Binding Sites
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Gene Deletion
- Histone Acetyltransferases
- Mutation
- Promoter Regions, Genetic
- Protein Binding
- Protein Kinases
- Saccharomyces cerevisiae Proteins
- Transcription Factor AP-1
- Transcription Factors
- Transcriptional Activation