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Article

Analysis of Gal4-directed transcription activation using Tra1 mutants selectively defective for interaction with Gal4.

Proceedings of the National Academy of Sciences of the United States of America - 7 Feb 2012

Lin Ling, Chamberlain Lynn, Zhu Lihua J, Green Michael R

Abstract excerpt

Promoter-specific transcriptional activators (activators) stimulate transcription through direct interactions with one or more components of the transcription machinery, termed the "target." The identification of direct in vivo targets of activators has been a major challenge. Previous studies have provided evidence that the Tra1 subunit of the yeast SAGA (Spt-Ada-Gcn5-acetyltransferase) complex is the target of...

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Identifiers

PMID: 22308403
DOI: 10.1073/pnas.1116340109
PMCID: PMC3277556

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