Article
GCN5, a yeast transcriptional coactivator, induces chromatin reconfiguration of HIS3 promoter in vivo.
Biochemical and biophysical research communications - 6 Jan 1998
Filetici P, Aranda C, Gonzàlez A, Ballario P
Abstract excerpt
Gcn5p, the nuclear histone acetyltransferase (HAT A), is a component of the multiprotein adaptor complex, ADA. Its role as a transcriptional coactivator is required for full induction of most of the genes regulated by GCN4. In this study we present experimental evidence demonstrating that, during...
Topics
- Chromatin
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Histone Acetyltransferases
- Hydro-Lyases
- Models, Genetic
- Mutation
- Nucleosomes
- Promoter Regions, Genetic
- Protein Kinases
- Saccharomyces cerevisiae Proteins
- Transcription Factors
- Transcriptional Activation
- Yeasts