Article
Transcriptional activation of yeast nucleotide biosynthetic gene ADE4 by GCN4.
The Journal of biological chemistry - 25 Oct 1991
Mösch H U, Scheier B, Lahti R, Mäntsäla P, Braus G H
Abstract excerpt
The yeast transcriptional regulator protein GCN4 harbors the bZIP DNA binding motif, which is common to a family of DNA-binding proteins in eukaryotic organisms from yeast to man. GCN4 and the mammalian activator protein AP-1 (jun/fos) regulate transcription by binding the same consensus DNA sequence ATGA (C/G)TCAT. GCN4 positively regulates the production of precursors of protein synthesis in yeast cells in...
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