Article
Two distinct yeast transcriptional activators require the function of the GCN5 protein to promote normal levels of transcription.
The EMBO journal - 1 Nov 1992
Georgakopoulos T, Thireos G
Abstract excerpt
When yeast cells are grown under conditions of amino acid limitation, transcription of amino acid biosynthetic genes is increased through the action of the GCN4 transcriptional regulator. gcn5 mutant strains exhibit poor growth under such conditions. We have established that GCN4 requires the fun...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA-Binding Proteins
- Drosophila
- Fungal Proteins
- Histone Acetyltransferases
- Humans
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oligodeoxyribonucleotides
- Phenotype
- Protein Biosynthesis
- Protein Kinases
- RNA, Messenger
- Recombinant Fusion Proteins
- Restriction Mapping