Article
Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation.
Molecular and cellular biology - 1 Jan 1997
Wang L, Mizzen C, Ying C, Candau R, Barlev N, Brownell J, Allis C D, Berger S L
Abstract excerpt
Yeast and human ADA2 and GCN5 (y- and hADA2 and y- and hGCN5, respectively) have been shown to potentiate transcription in vivo and may function as adaptors to bridge physical interactions between DNA-bound activators and the basal transcriptional machinery. Recently it was shown that yGCN5 is a...
Topics
- Acetylation
- Acetyltransferases
- DNA-Binding Proteins
- Fungal Proteins
- Genetic Complementation Test
- Glutathione Transferase
- Herpes Simplex Virus Protein Vmw65
- Histone Acetyltransferases
- Histones
- Humans
- Mutation
- Protein Kinases
- Recombinant Fusion Proteins