Article
The Gcn5.Ada complex potentiates the histone acetyltransferase activity of Gcn5.
The Journal of biological chemistry - 18 Sept 1998
Syntichaki P, Thireos G
Abstract excerpt
The Gcn5 histone acetyltransferase (HAT) is part of a large multimeric complex that is required for transcriptional activation in yeast. This complex can acetylate in vitro and in a Gcn5-dependent manner both nucleosomal and free core histones. For this reason it is believed that part of the func...
Topics
- Acetyltransferases
- Cloning, Molecular
- DNA-Binding Proteins
- Escherichia coli
- Fungal Proteins
- Genetic Complementation Test
- Histone Acetyltransferases
- Kinetics
- Multienzyme Complexes
- Mutagenesis, Site-Directed
- Nucleosomes
- Phenotype
- Point Mutation
- Polymerase Chain Reaction
- Protein Kinases
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins