Article
Novel mutation in the first intron of the spontaneously hypertensive rat renin gene upstream of the tandem repeat element.
Clinical and experimental pharmacology & physiology. Supplement - 1 Dec 1995
Di Nicolantonio R, Yu H, Wilks A, Lan L
Abstract excerpt
1. The first 1100 base pairs of the first intron of the renin gene was amplified from the spontaneously hypertensive rat (SHR), Wistar-Kyoto (WKY) and Sprague-Dawley (SD) rats. A Bgl II restriction fragment length polymorphism (RFLP) was identified in this region of the SHR renin gene. 2. Sequenc...
Topics
- Animals
- Base Sequence
- DNA
- Hypertension
- Introns
- Molecular Sequence Data
- Mutation
- Polymorphism, Restriction Fragment Length
- Rats
- Rats, Inbred SHR
- Rats, Inbred WKY
- Rats, Sprague-Dawley
- Renin
- Repetitive Sequences, Nucleic Acid
