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Article

Structural alterations of the renin gene in stroke-prone spontaneously hypertensive rats: examination of genotype-phenotype correlations.

Journal of hypertension - 1 Aug 1990

Lindpaintner K, Takahashi S, Ganten D

Abstract excerpt

Primary hypertension is considered a polygenic, inherited disorder; to date, the nature of the genes involved remains unknown. In this study we present evidence for a structural difference in the gene coding for renin between the stroke-prone, spontaneously hypertensive rat (SHRSP) and its normotensive control, the Wistar-Kyoto rat (WKY). Restriction fragment analysis using hybridization against probes...

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PMID: 1976691
DOI: 10.1097/00004872-199008000-00011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structural alterations of the renin gene in stroke-prone spontaneously hypertensive rats: examination of genotype-phenotype correlations.PMID 1976691Read ↗

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Altered structure, regulation, and function of the gene encoding the atrial natriuretic peptide in the stroke-prone spontaneously hypertensive rat.Semantic proximity Read ↗

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Cosegregation of the renin gene with an increase in mean arterial blood pressure in the F2 rats of SHR-WKY cross.Semantic proximity Read ↗

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