Article
Analysis of the renin gene intron A tandem repeat region of Milan and Lyon hypertensive rat strains.
Journal of hypertension - 1 Sept 1990
Samani N J, Vincent M, Sassard J, Henderson I W, Kaiser M A, Brammar W J, Swales J D
Abstract excerpt
The region of intron A of the rat renin gene containing a unique tandemly repeated sequence was analysed in the Milan and Lyon hypertensive rat strains and their controls, and in several Sprague-Dawley rats, using an oligonucleotide probe complementary to the tandemly repeated sequence and a renin complementary DNA probe. In the Milan rats, the size of the Bgl II DNA fragment encompassing the tandem repeat region...
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