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Article

Cosegregation of the renin allele of the spontaneously hypertensive rat with an increase in blood pressure.

The Journal of clinical investigation - 1 Apr 1990

Kurtz T W, Simonet L, Kabra P M, Wolfe S, Chan L, Hjelle B L

Abstract excerpt

The spontaneously hypertensive rat (SHR) exhibits alterations in the renin-angiotensin-aldosterone system which are similar to those that characterize patients with "nonmodulating" hypertension, a common and highly heritable form of essential hypertension. Accordingly, we determined whether the inheritance of a DNA restriction fragment length polymorphism (RFLP) marking the renin gene of the SHR was associated...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 1969424
DOI: 10.1172/JCI114572
PMCID: PMC296571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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