Article
Identification and genetic mapping of a new polycystic kidney disease on mouse chromosome 8.
Genomics - 15 Feb 1997
Janaswami P M, Birkenmeier E H, Cook S A, Rowe L B, Bronson R T, Davisson M T
Abstract excerpt
We report here a new mouse mutation, kat, that causes pleiotropic effects including facial dysmorphism, dwarfing, male sterility, anemia, and progressive polycystic kidney disease. kat (kidney anemia and testis) and a second allele, kat2J, that occurred on C57BL/ 6J were mapped to mouse chromosome (Chr) 8 using intra- and intersubspecific intercrosses. A high-resolution map for kat2J on Chr 8 was constructed...
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