Article
Clinical and pathologic findings in two new allelic murine models of polycystic kidney disease.
Journal of the American Society of Nephrology : JASN - 1 Dec 1999
Vogler C, Homan S, Pung A, Thorpe C, Barker J, Birkenmeier E H, Upadhya P
Abstract excerpt
Patients with inherited cystic kidney diseases have progressive cystic dilation of nephrons with concomitant loss of functional renal parenchyma and renal failure. Animal models of inherited cystic kidney disease are useful for study of the pathogenesis and molecular basis of cystic renal diseases. This article describes the clinical and pathologic features in two spontaneously occurring murine models of...
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