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Article

The mouse polycystic kidney disease mutation (cpk) is located on proximal chromosome 12.

Genomics - 1 Apr 1991

Davisson M T, Guay-Woodford L M, Harris H W, D'Eustachio P

Abstract excerpt

The mouse congenital polycystic kidney (cpk) mutation produces a condition that resembles human autosomal recessive polycystic kidney disease (ARPKD) in its pattern of inheritance, clinical progression, and histopathology. Inheritance of this mouse mutation in crosses segregating the Rb(12.14)8Rma translocation chromosome and various DNA markers of Chromosome 12 have localized cpk to a site near D12Nyu2,...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Female
Genetic Linkage
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Mutation
Polycystic Kidney Diseases
Translocation, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2037305
DOI: 10.1016/0888-7543(91)90376-p

Genes

PKD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2037305-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The mouse polycystic kidney disease mutation (cpk) is located on proximal chromosome 12.PMID 2037305Read ↗

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