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Article

Evidence that two phenotypically distinct mouse PKD mutations, bpk and jcpk, are allelic.

Kidney international - 1 Oct 1996

Guay-Woodford L M, Bryda E C, Christine B, Lindsey J R, Collier W R, Avner E D, D'Eustachio P, Flaherty L

Abstract excerpt

Numerous mouse models of polycystic kidney disease (PKD) have been described. All of these diseases are transmitted as single recessive traits and in most, the phenotypic severity is influenced by the genetic background. However, based on their genetic map positions, none of these loci appears to be allelic and none are candidate modifier loci for any other mouse PKD mutation. Previously, we have described the...

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Source

Identifiers

PMID: 8887273
DOI: 10.1038/ki.1996.423

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Evidence that two phenotypically distinct mouse PKD mutations, bpk and jcpk, are allelic.PMID 8887273Read ↗

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Genetic modifiers of polycystic kidney disease in intersubspecific KAT2J mutants.Semantic proximity Read ↗

Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway.Semantic proximity Read ↗

Phenotypic variations of orpk mutation and chromosomal localization of modifiers influencing kidney phenotype.Semantic proximity Read ↗

Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse.Semantic proximity Read ↗

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Genetic localization of interacting modifiers affecting severity in a murine model of polycystic kidney disease.Semantic proximity Read ↗

Murine autosomal recessive polycystic kidney disease with multiorgan involvement induced by thecpk geneSemantic proximity Read ↗

Genetic analysis of modifying loci on mouse chromosome 1 that affect disease severity in a model of recessive PKD.Semantic proximity Read ↗

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