Article
Evidence that two phenotypically distinct mouse PKD mutations, bpk and jcpk, are allelic.
Kidney international - 1 Oct 1996
Guay-Woodford L M, Bryda E C, Christine B, Lindsey J R, Collier W R, Avner E D, D'Eustachio P, Flaherty L
Abstract excerpt
Numerous mouse models of polycystic kidney disease (PKD) have been described. All of these diseases are transmitted as single recessive traits and in most, the phenotypic severity is influenced by the genetic background. However, based on their genetic map positions, none of these loci appears to...
Topics
- Alleles
- Animals
- Animals, Newborn
- Chromosome Mapping
- Crosses, Genetic
- Disease Models, Animal
- Female
- Genetic Complementation Test
- Kidney
- Male
- Mice
- Mice, Inbred BALB C
- Mutation
- Phenotype
- Polycystic Kidney Diseases
- Recombination, Genetic
