Article
A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2006
Nakayama Manabu, Iida Midori, Koseki Haruhiko, Ohara Osamu
Abstract excerpt
Given that thousands of genes exist in the mammalian genome, criteria are needed to prioritize their functional analysis and to decrease the likelihood of producing gene-targeted mice that lack overt phenotypes. Initial analysis efforts are likely to be fruitful if focused on genes encoding large...
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