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Article

Genetic modifiers of polycystic kidney disease in intersubspecific KAT2J mutants.

Genomics - 1 Jun 1999

Upadhya P, Churchill G, Birkenmeier E H, Barker J E, Frankel W N

Abstract excerpt

Polycystic kidney disease (PKD) is a genetically heterogeneous disorder. In addition to the many PKD-causative loci mapped in mouse and human, a number of reports indicate that modifier loci greatly influence the course of disease progression. Recently we reported a new mouse mutation, kat2J, on chromosome (Chr) 8 that causes late-onset PKD and anemia. During the mapping studies it was noted that the severity of...

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PMID: 10366444
DOI: 10.1006/geno.1999.5830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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