Article
An integrated genetic and physical map of the 650-kb region containing the congenital polycystic kidney (cpk) locus on mouse chromosome 12.
Cytogenetics and cell genetics - 1 Jan 2001
Mrug M, Green W J, DasGupta S, Beier D R, Lu W, D'Eustachio P, Guay-Woodford L M
Abstract excerpt
Mice homozygous for the congenital polycystic kidney (cpk) mutation develop a rapidly progressive form of polycystic kidney disease. We report an integrated genetic and physical map of the 650-kb region containing the cpk locus and the exclusion of Rrm2 and Idb2 as candidate cpk genes. Our study establishes the requisite foundation for positional cloning of the cpk gene.
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