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Article

The mouse kinome: discovery and comparative genomics of all mouse protein kinases.

Proceedings of the National Academy of Sciences of the United States of America - 10 Aug 2004

Caenepeel Sean, Charydczak Glen, Sudarsanam Sucha, Hunter Tony, Manning Gerard

Abstract excerpt

We have determined the full protein kinase (PK) complement (kinome) of mouse. This set of 540 genes includes many novel kinases and corrections or extensions to >150 published sequences. The mouse has orthologs for 510 of the 518 human PKs. Nonorthologous kinases arise only by retrotransposition and gene decay. Orthologous kinase pairs vary in sequence conservation along their length, creating a map of...

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Identifiers

PMID: 15289607
DOI: 10.1073/pnas.0306880101
PMCID: PMC511041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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