The mouse congenital polycystic kidney (cpk) locus maps within 1.3 cM of the chromosome 12 marker D12Nyu2.

doi:10.1006/geno.1994.1285

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Article

The mouse congenital polycystic kidney (cpk) locus maps within 1.3 cM of the chromosome 12 marker D12Nyu2.

Genomics - 15 May 1994

Simon E A, Cook S, Davisson M T, D'Eustachio P, Guay-Woodford L M

Abstract excerpt

The mouse congenital polycystic kidney (cpk) mutation causes bilateral cystic dilatation of the renal collecting tubules and leads to rapidly progressive renal insufficiency in affected homozygotes. The phenotype of the cpk/cpk mutants closely resembles that of human autosomal recessive polycysti...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Female
Genetic Linkage
Genetic Markers
Humans
Male
Mice
Mice, Inbred C57BL
Mice, Mutant Strains
Mutation
Polycystic Kidney Diseases
Recombination, Genetic

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