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Article

Overexpression of p53 mRNA in colorectal cancer and its relationship to p53 gene mutation.

British journal of cancer - 1 Jan 1997

el-Mahdani N, Vaillant J C, Guiguet M, Prévot S, Bertrand V, Bernard C, Parc R, Béréziat G, Hermelin B

Abstract excerpt

We analysed the frequency of p53 mRNA overexpression in a series of 109 primary colorectal carcinomas and its association with p53 gene mutation, which has been correlated with short survival. Sixty-nine of the 109 cases (63%) demonstrated p53 mRNA overexpression, without any correlation with stage or site of disease. Comparison with p53 gene mutation indicated that, besides cases in which p53 gene mutation and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 9052405
DOI: 10.1038/bjc.1997.92
PMCID: PMC2063311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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