Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 accumulation and mutation are prognostic indicators of poor survival in human gastric carcinoma.

International journal of cancer - 21 Jun 1996

Lim B H, Soong R, Grieu F, Robbins P D, House A K, Iacopetta B J

Abstract excerpt

The aim of our study was to examine the prognostic significance of p53 protein accumulation and gene mutation in a series of 116 gastric carcinomas from a low incidence population. Formalin-fixed, paraffin-embedded tumour sections were used to investigate p53 protein accumulation by immunostaining with monoclonal antibody (MAb) DO-7 and p53 gene mutation by single-strand conformation polymorphism analysis of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Genes, p53

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Mutation

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 8682588
DOI: 10.1002/(SICI)1097-0215(19960621)69:3<200::AID-IJC9>3.0.CO;2-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 accumulation and mutation are prognostic indicators of poor survival in human gastric carcinoma.PMID 8682588Read ↗

p53 protein accumulation and p53 gene mutation in esophageal carcinoma. A molecular and immunohistochemical study with clinicopathologic correlations.Semantic proximity Read ↗

p53 alterations are associated with improved prognosis in distal colonic carcinomas.Semantic proximity Read ↗

Genetic and immunohistochemical analyses of p53 independently predict regional metastasis of gastric cancers.Semantic proximity Read ↗

Accumulation of p53 tumor suppressor gene protein: an independent marker of prognosis in breast cancers.Semantic proximity Read ↗

Comparative analysis of p53 gene mutations and protein accumulation in human non-small-cell lung cancer.Semantic proximity Read ↗

p53 protein accumulation and p53 gene mutation in colorectal cancer.Semantic proximity Read ↗

p53 alterations in oesophageal cancer: association with clinicopathological features, risk factors, and survival.Semantic proximity Read ↗

TP53 and gastric carcinoma: a review.Semantic proximity Read ↗

p53 gene mutation and protein accumulation during neoplastic progression in Barrett's esophagus.Semantic proximity Read ↗

Prediction of TP53 mutations by p53 immunohistochemistry and their prognostic significance in gastric cancerSemantic proximity Read ↗

Concordance between p53 protein overexpression and gene mutation in a large series of common human carcinomas.Semantic proximity Read ↗

Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.