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Article

Molecular modelling of HLA-DQ suggests a mechanism of resistance in type 1 diabetes.

Scandinavian journal of immunology - 1 Feb 1997

Hoover M L, Marta R T

Abstract excerpt

Genetic resistance and susceptibility to insulin-dependent diabetes mellitus (IDDM) have been associated with the HLA class II region on chromosome 6. In many races, the DQB1*0602 allele has been observed at a decreased frequency in IDDM, suggesting a protective role. A DNA sequence analysis of five patients, previously typed as having allele DQB1*0602, revealed sequence variation: one is DQB1*0603 and four...

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Source

Identifiers

PMID: 9042432
DOI: 10.1046/j.1365-3083.1997.d01-389.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular modelling of HLA-DQ suggests a mechanism of resistance in type 1 diabetes.PMID 9042432Read ↗

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