Article
Demonstration of p53 protein and TP53 gene mutations in oligodendrogliomas.
European journal of cancer (Oxford, England : 1990) - 1 Dec 1996
Hagel C, Laking G, Laas R, Scheil S, Jung R, Milde-Langosch K, Stavrou D K
Abstract excerpt
Paraffin embedded tissue of 84 oligodendrogliomas (63 primary tumours, 21 recurrences), 21 glioblastomas with oligodendroglial growth pattern (15 primaries, 6 recurrences) and 17 mixed gliomas was investigated for the presence of mutations in exons 5-9 by means of single stranded conformation polymorphism (SCCP), temperature gradient gel electrophoresis (TGGE) and direct DNA sequencing. In parallel, p53 protein...
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