Demonstration of p53 protein and TP53 gene mutations in oligodendrogliomas.

doi:10.1016/s0959-8049(96)00259-6

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Article

Demonstration of p53 protein and TP53 gene mutations in oligodendrogliomas.

European journal of cancer (Oxford, England : 1990) - 1 Dec 1996

Hagel C, Laking G, Laas R, Scheil S, Jung R, Milde-Langosch K, Stavrou D K

Abstract excerpt

Paraffin embedded tissue of 84 oligodendrogliomas (63 primary tumours, 21 recurrences), 21 glioblastomas with oligodendroglial growth pattern (15 primaries, 6 recurrences) and 17 mixed gliomas was investigated for the presence of mutations in exons 5-9 by means of single stranded conformation pol...

Topics

Adult
Brain Neoplasms
Female
Genes, p53
Humans
Immunoenzyme Techniques
Male
Middle Aged
Mutation
Neoplasm Proteins
Oligodendroglioma
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 9038605
DOI: 10.1016/s0959-8049(96)00259-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9038605-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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