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Article

The hepatitis B virus core and e antigens elicit different Th cell subsets: antigen structure can affect Th cell phenotype.

Journal of virology - 1 Mar 1997

Milich D R, Schödel F, Hughes J L, Jones J E, Peterson D L

Abstract excerpt

Secretion of the hepatitis B virus (HBV) e antigen (HBeAg) has been conserved throughout the evolution of hepadnaviruses. However, the function of this secreted form of the viral nucleoprotein remains enigmatic. It has been suggested that HBeAg functions as an immunomodulator. We therefore examined the possibility that the two structural forms of the viral nucleoprotein, the particulate HBV core (HBcAg) and the...

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Identifiers

PMID: 9032353
DOI: 10.1128/JVI.71.3.2192-2201.1997
PMCID: PMC191326

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Source receipt: pubmed, retrieved 7 Sept 2026.

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