Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection.

doi:10.1053/jhep.2003.50453

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Article

Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection.

Hepatology (Baltimore, Md.) - 1 Nov 2003

Milich David, Liang T Jake

Abstract excerpt

The function of the hepatitis B e antigen (HBeAg) is largely unknown because it is not required for viral assembly, replication, or infection. In this report we chronicle clinical and experimental studies in an attempt to understand the role of HBeAg in natural infection. These studies largely have focused on clinical-pathologic features of HBeAg-negative variants in acute and chronic HBV infection, mutational...

Topics

Animals
Antiviral Agents
Genetic Variation
Hepatitis B
Hepatitis B Core Antigens
Hepatitis B e Antigens
Hepatitis B virus
Humans
Immunosuppressive Agents
Infectious Disease Transmission, Vertical
Molecular Biology
Organic Chemicals

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Open in PubMed

Identifiers

PMID: 14578844
DOI: 10.1053/jhep.2003.50453

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