Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection.

doi:10.1128/JVI.69.6.3358-3368.1995

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Article

Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection.

Journal of virology - 1 Jun 1995

Jung M C, Diepolder H M, Spengler U, Wierenga E A, Zachoval R, Hoffmann R M, Eichenlaub D, Frösner G, Will H, Pape G R

Abstract excerpt

Overcoming hepatitis B virus infection essentially depends on the appropriate immune response of the infected host. Among the hepatitis B virus antigens, the core (HBcAg) and e (HBeAg) proteins appear highly immunogenic and induce important lymphocyte effector functions. In order to investigate t...

Topics

Acute Disease
Base Sequence
CD4-Positive T-Lymphocytes
Chronic Disease
Clone Cells
DNA Primers
Epitopes
Hepatitis B
Hepatitis B Antibodies
Hepatitis B Core Antigens
Hepatitis B e Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatitis B virus

Humans

Lymphokines

Molecular Sequence Data

Mutation

Phenotype

Source

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Identifiers

PMID: 7538172
DOI: 10.1128/JVI.69.6.3358-3368.1995
PMCID: PMC189048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7538172-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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