Article
Protective efficacy, immunotherapeutic potential, and safety of hepatitis B vaccines.
Journal of medical virology - 1 Feb 2006
Zuckerman Jane N
Abstract excerpt
Hepatitis B vaccines are highly effective and safe and have been incorporated into national immunization programs in over 150 countries. The major humoral immune response is to the common a determinant of the surface antigen protein of the virus. Approximately 5-10% of healthy immunocompetent subjects do not mount an antibody response (anti-HBs). Non-response is associated with different HLA-DR alleles and...
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