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DNA double-strand-break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 4 Feb 1997

Barnes G, Rio D

Abstract excerpt

In mammalian cells, the Ku heterodimer is involved in DNA double-strand-break recognition and repair. We have established in yeast a connection between Ku activity and DNA double-strand-break damage repair, and a connection between Ku activity and commitment to DNA replication. We generated doubl...

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Mutation
DNA-Binding Proteins
Fungal Proteins
Genetic Complementation Test
Drosophila melanogaster
Nuclear Proteins

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PMID: 9023348
DOI: 10.1073/pnas.94.3.867
PMCID: PMC19605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9023348-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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