Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A protein-counting mechanism for telomere length regulation in yeast.

Science (New York, N.Y.) - 14 Feb 1997

Marcand S, Gilson E, Shore D

Abstract excerpt

In the yeast Saccharomyces cerevisiae, telomere elongation is negatively regulated by the telomere repeat-binding protein Rap1p, such that a narrow length distribution of telomere repeat tracts is observed. This length regulation was shown to function independently of the orientation of the telomere repeats. The number of repeats at an individual telomere was reduced when hybrid proteins containing the Rap1p...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Fungal Proteins
Share to Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to GTP-Binding Proteins

Share to Mutation

Share to Saccharomyces cerevisiae

Share to Transformation, Genetic

Source

Identifiers

PMID: 9020083
DOI: 10.1126/science.275.5302.986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A protein-counting mechanism for telomere length regulation in yeast.PMID 9020083Read ↗

Rap1 protein regulates telomere turnover in yeast.Semantic proximity Read ↗

A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.Semantic proximity Read ↗

C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae.Semantic proximity Read ↗

Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length.Semantic proximity Read ↗

Varying the number of telomere-bound proteins does not alter telomere length in tel1Delta cells.Semantic proximity Read ↗

Regulation of Telomere Length Requires a Conserved N-Terminal Domain of Rif2 in Saccharomyces cerevisiae.Semantic proximity Read ↗

Telomeric protein distributions and remodeling through the cell cycle in Saccharomyces cerevisiae.Semantic proximity Read ↗

Regulation of telomere length by an N-terminal region of the yeast telomerase reverse transcriptase.Semantic proximity Read ↗

A novel mechanism for telomere size control in Saccharomyces cerevisiae.Semantic proximity Read ↗

A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.Semantic proximity Read ↗

Budding yeast Rap1, but not telomeric DNA, is inhibitory for multiple stages of DNA replication in vitroSemantic proximity Read ↗

Rif1 acts through Protein Phosphatase 1 but independent of replication timing to suppress telomere extension in budding yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.