Article
Varying the number of telomere-bound proteins does not alter telomere length in tel1Delta cells.
Proceedings of the National Academy of Sciences of the United States of America - 21 Dec 1999
Ray A, Runge K W
Abstract excerpt
Yeast telomere DNA consists of a continuous, approximately 330-bp tract of the heterogeneous repeat TG(1-3) with irregularly spaced, high affinity sites for the protein Rap1p. Yeast monitor, or count, the number of telomeric Rap1p C termini in a negative feedback mechanism to modulate the length of the terminal TG(1-3) repeats, and synthetic telomeres that tether Rap1p molecules adjacent to the TG(1-3) tract...
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