Article
CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication.
Molecular and cellular biology - 1 Feb 1997
Zou L, Mitchell J, Stillman B
Abstract excerpt
The CDC45 gene of Saccharomyces cerevisiae was isolated by complementation of the cold-sensitive cdc45-1 mutant and shown to be essential for cell viability. Although CDC45 genetically interacts with a group of MCM genes (CDC46, CDC47, and CDC54), the predicted sequence of its protein product rev...
Topics
- Amino Acid Sequence
- Base Sequence
- Carrier Proteins
- Cell Cycle Proteins
- Cloning, Molecular
- Crosses, Genetic
- DNA Replication
- DNA, Fungal
- DNA-Binding Proteins
- Genes, Fungal
- Genes, Lethal
- Mating Factor
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Peptides
- Plasmids
- Replication Origin