Article
SpSld3 is required for loading and maintenance of SpCdc45 on chromatin in DNA replication in fission yeast.
Molecular biology of the cell - 1 May 2002
Nakajima Reiko, Masukata Hisao
Abstract excerpt
Initiation of DNA replication in eukaryotic cells is regulated through the ordered assembly of replication complexes at origins of replication. Association of Cdc45 with the origins is a crucial step in assembly of the replication machinery, hence can be considered a target for the regulation of origin activation. To examine the process required for SpCdc45 loading, we isolated fission yeast SpSld3, a counterpart...
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