Article
The essential schizosaccharomyces pombe cdc23 DNA replication gene shares structural and functional homology with the Saccharomyces cerevisiae DNA43 (MCM10) gene.
Current genetics - 1 Sept 1998
Aves S J, Tongue N, Foster A J, Hart E A
Abstract excerpt
The fission yeast cdc23 gene is required for correct DNA replication: cdc23 mutants show reduced rates of DNA synthesis and become elongated after cell-cycle arrest. We have cloned the Schizosaccharomyces pombe cdc23 gene by complementation of the temperature-sensitive phenotype of cdc23-M36 and...
Topics
- Amino Acid Sequence
- Anaphase-Promoting Complex-Cyclosome
- Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome
- Cell Cycle Proteins
- Chromosomal Proteins, Non-Histone
- Cloning, Molecular
- DNA Replication
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test
- Microscopy, Fluorescence
- Minichromosome Maintenance Proteins
- Molecular Sequence Data