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Article

A novel, transformation-relevant activation domain in Fos proteins.

Molecular and cellular biology - 1 Feb 1997

Funk M, Poensgen B, Graulich W, Jerome V, Müller R

Abstract excerpt

We have previously demonstrated that transformation by Fos is critically dependent on an intact DNA-binding domain (bZip) and a functional N-terminal transactivation motif (N-TM). We now show that a novel motif (C-terminal transactivation motif [C-TM]) near the C terminus also plays an important role in both transformation and the activation of AP1-dependent transcription and that the hydrophobic amino acids in...

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Identifiers

PMID: 9001206
DOI: 10.1128/MCB.17.2.537
PMCID: PMC231778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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