Article
EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains.
The EMBO journal - 15 Jun 1995
Hagman J, Gutch M J, Lin H, Grosschedl R
Abstract excerpt
Early B cell factor (EBF) was identified and cloned as a transcription factor expressed specifically in B lymphocytes and adipocytes. This protein was also identified as olfactory factor 1 (Olf-1) in olfactory neurons. In this study, we analyzed the structural requirements for DNA binding, homodimerization and transcriptional activation by EBF. A carboxyl-terminal region, containing a repeat of alpha-helices...
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