The C-terminal domain of c-fos is required for activation of an AP-1 site specific for jun-fos heterodimers.

doi:10.1128/MCB.18.9.5073

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Article

The C-terminal domain of c-fos is required for activation of an AP-1 site specific for jun-fos heterodimers.

Molecular and cellular biology - 1 Sept 1998

McBride K, Nemer M

Abstract excerpt

The proto-oncogenes jun and fos are members of the AP-1 family of transcription factors, which activate transcription of target genes via the tetradecanoyl phorbol acetate response element (TRE). Both jun and fos contain activation domains, but their relative contributions to transcriptional activation of different TREs remain unclear. It is not apparent whether the cellular availability of specific AP-1 members...

Topics

Animals
Atrial Natriuretic Factor
Base Sequence
Calcium-Calmodulin-Dependent Protein Kinases
Cell Line
Cell Nucleus
Cells, Cultured
DNA-Binding Proteins
Dimerization
Fungal Proteins
Genes, fos

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, jun

HeLa Cells

Humans

Mutation

Myocardium

Promoter Regions, Genetic

Proto-Oncogene Proteins c-fos

Source

Open in PubMed Open full text

Identifiers

PMID: 9710591
DOI: 10.1128/MCB.18.9.5073
PMCID: PMC109092

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The C-terminal domain of c-fos is required for activation of an AP-1 site specific for jun-fos heterodimers.PMID 9710591Read ↗

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