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Article

The transcription factor Fos: a Janus-type regulator in health and disease.

1 Nov 2009

Abstract excerpt

The immediate early gene product Fos is part of the activator protein-1 (AP-1) transcription factor and has been shown to participate in the molecular mechanisms of cell proliferation, differentiation, apoptosis, and transformation. The analysis of genetically modified mice and cells derived thereof has provided important new insights into its specific biological functions in development, tissue homeostasis, and...

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PMID: 19760594
DOI: 10.14670/hh-24.1451

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