Article
An autonomous N-terminal transactivation domain in Fos protein plays a crucial role in transformation.
The EMBO journal - 15 Mar 1994
Jooss K U, Funk M, Müller R
Abstract excerpt
To date, three functional domains have been defined in c-Fos and v-Fos proteins and have been shown to play a role in transactivation: the leucine zipper mediating hetero-dimerization, the basic DNA contact site, and a C-terminally located transactivation domain (C-TA) harbouring the HOB1 and HOB2 motifs. While the bZip region, consisting of the leucine zipper and the DNA contact site, is indispensable for...
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