Analysis of VH gene diversity in rainbow trout (Oncorhynchus mykiss): both nonsynonymous and synonymous nucleotide changes are more frequent in CDRs than in FRs.

doi:10.1007/s002510050190

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Article

Analysis of VH gene diversity in rainbow trout (Oncorhynchus mykiss): both nonsynonymous and synonymous nucleotide changes are more frequent in CDRs than in FRs.

Immunogenetics - 1 Jan 1997

Matsunaga T, Andersson E

Abstract excerpt

Forty-six immunoglobulin VH gene sequences of rainbow trout were compiled to analyze the extent of variations and the frequency of nucleotide changes in CDRs and FRs. The results show that the frequency of nonsynonymous (amino acid replacing) changes (Ka) are on average 4.9 times higher in comple...

Topics

Animals
Genetic Variation
Immunoglobulin Heavy Chains
Immunoglobulin Variable Region
Mice
Oncorhynchus mykiss
Sharks

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