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Article

Structure and diversity of the TCR α-chain in a teleost fish

1 Jul 1996

Abstract excerpt

T cell receptor beta-chain genes are well characterized in representatives of most vertebrate phyla, from sharks to mammals, but the molecular structure of complete TCR alpha-chains has not yet been established in cold-blooded vertebrates. We used a PCR approach to isolate cDNAs encoding putative teleost fish (Oncorhynchus mykiss, rainbow trout) TCR alpha-chains. Eight V alpha segments were identified, belonging...

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PMID: 8683116
DOI: 10.4049/jimmunol.157.1.207

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