Article
Inter- and intraspecies comparison of phylogenetic fingerprints and sequence diversity of immunoglobulin variable genes.
Immunogenetics - 1 Jul 2020
Yermanos Alexander, Dounas Andreas, Greiff Victor, Stadler Tanja, Oxenius Annette, Reddy Sai T
Abstract excerpt
Protection and neutralization of a vast array of pathogens is accomplished by the tremendous diversity of the B cell receptor (BCR) repertoire. For jawed vertebrates, this diversity is initiated via the somatic recombination of immunoglobulin (Ig) germline elements. While it is clear that the number of these germline segments differs from species to species, the extent of cross-species sequence diversity remains...
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