Article
Immunoglobulin variable-region diversity in the zebrafish.
Immunogenetics - 1 Nov 2000
Danilova N, Hohman V S, Kim E H, Steiner L A
Abstract excerpt
As part of an investigation of the immune system in the developing zebrafish, Danio rerio, we cloned and characterized a genomic V(H) segment and a number of cDNAs encoding IgM heavy chains. The genomic V(H) has the characteristic features of V(H) in other vertebrates, including a leader segment interrupted by a short intron, and regulatory and recombination signal sequences. The V(H) sequences of 75 cDNA clones...
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