Article
Memory B lymphocytes migrate to bone marrow in humans.
Proceedings of the National Academy of Sciences of the United States of America - 7 Jan 1997
Paramithiotis E, Cooper M D
Abstract excerpt
IgM-bearing B lymphocytes with mature phenotype (CD10- CD24(lo) IgD+) are acquired after birth in the bone marrow of humans. These B cells are defined here as relatively large, nondividing lymphocytes, variable proportions of which express cell surface molecules indicative of relatively recent activation. Analysis of V(H)5(2) (heavy chain variable region) gene transcripts indicated point mutations throughout the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
