Article
Surface phenotypes of naive and memory B cells in mouse and human tissues.
Nature immunology - 1 Jan 2022
Weisel Nadine M, Joachim Stephen M, Smita Shuchi, Callahan Derrick, Elsner Rebecca A, Conter Laura J, Chikina Maria, Farber Donna L, Weisel Florian J, Shlomchik Mark J
Abstract excerpt
Memory B cells (MBCs) protect the body from recurring infections. MBCs differ from their naive counterparts (NBCs) in many ways, but functional and surface marker differences are poorly characterized. In addition, although mice are the prevalent model for human immunology, information is limited concerning the nature of homology in B cell compartments. To address this, we undertook an unbiased, large-scale...
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