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Article

Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways.

Blood - 25 Aug 2011

Berkowska Magdalena A, Driessen Gertjan J A, Bikos Vasilis, Grosserichter-Wagener Christina, Stamatopoulos Kostas, Cerutti Andrea, He Bing, Biermann Katharina, Lange Johan F, van der Burg Mirjam, van Dongen Jacques J M, van Zelm Menno C

Abstract excerpt

Multiple distinct memory B-cell subsets have been identified in humans, but it remains unclear how their phenotypic diversity corresponds to the type of responses from which they originate. Especially, the contribution of germinal center-independent responses in humans remains controversial. We defined 6 memory B-cell subsets based on their antigen-experienced phenotype and differential expression of CD27 and IgH...

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Identifiers

PMID: 21690558
DOI: 10.1182/blood-2011-04-345579
PMCID: PMC3342861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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