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Free ricin A chain reaches an early compartment of the secretory pathway before it enters the cytosol.

Experimental cell research - 15 Dec 1996

Simpson J C, Roberts L M, Lord J M

Abstract excerpt

During the intoxication of mammalian cells by ricin, the catalytically active A chain must cross the membrane of an intracellular compartment in order to reach its ribosomal substrates in the cytosol. The actual site of ricin A chain translocation is unclear, and conflicting views hold that it enters the cytosol from endosomes or from an early compartment of the secretory pathway, possibly the lumen of the...

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Identifiers

PMID: 8986628
DOI: 10.1006/excr.1996.0390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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