Article
Analysis of cleavage site mutations between the NC and PR Gag domains of Rous sarcoma virus.
Journal of virology - 1 Jan 1997
Schatz G, Pichova I, Vogt V M
Abstract excerpt
In retroviruses, the viral protease (PR) is released as a mature protein by cleavage of Gag, Gag-Pro, or Gag-Pro-Pol precursor polypeptides. In avian sarcoma and leukemia viruses (ASLV), PR forms the C-terminal domain of Gag. Based on the properties of a mutation (cs22) in the cleavage site betwe...
Topics
- Animals
- Avian Sarcoma Viruses
- Binding Sites
- COS Cells
- Endopeptidases
- Gene Products, gag
- Mutation
- Peptides
- Protein Biosynthesis
- Protein Processing, Post-Translational
- Retroviridae Proteins
- Transfection
