Article
Avian sarcoma leukemia virus protease linked to the adjacent Gag polyprotein is enzymatically active.
Virology - 20 Dec 1995
Arad G, Bar-Meir R, Almog N, Chorev M, Kotler M
Abstract excerpt
The activity of avian sarcoma leukemia virus (ASLV) protease (PR) prior to its release from the precursor protein was determined by introducing mutations at the cleavage site between PR and the adjacent upstream nucleocapsid (NC) protein. Gag DNA fragments containing these mutations were cloned i...
Topics
- Animals
- Avian Sarcoma Viruses
- Binding Sites
- Catalysis
- Endopeptidases
- Escherichia coli
- Gene Expression Regulation, Viral
- Gene Products, gag
- Mutation
- Peptides
- Protein Processing, Post-Translational
- Recombinant Proteins
- Substrate Specificity
- Viral Core Proteins